Researchers at The University of Queensland have shown that the calcium release-activated calcium (CRAC) channels, and in particular CRACM1, are over-expressed by breast cancers.  Using both an RNAi approach and a commercially available molecule inhibitor of CRACM1, they have shown that inhibition of CRACM1 inhibits the proliferation of breast cancer cells.  The technology aims to address all breast cancer patients, since tumour cells require calcium to regulate normal cellular processes.

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